Write a personal mission statement. That helps you decide what prioritize.
My personal mission statement is "Make as big a difference as possible regarding career advice, education advice, men's issues, gifted kids, exposing higher education as America's most overrated product, and encouraging an honest national conversation about race."
Have a time-conscious voice on your shoulder. I'm always asking myself, "Is this a good use of my time?" and "Am I doing this in the most time-effective way?"
Avoid time sucks. For example, could you get out of attending that meeting, especially a standing meeting? Also, of course, watch for after-work time sucks: TV watching, golf, trekking to a relative's bar mitzvah.
Delegate. It's often worth delegating even if the task won't be done as well. That frees you up to do other more profitable or pleasurable activities.
Hire a personal assistant. Even a few hours a week at $10 an hour will buy you significant time you could use more profitably than doing your laundry or getting your car's oil changed.
Get observed. Not sure how to get more time-efficient? Get someone who gets a lot done to watch you for an hour or more.
Class dismissed. Anyone wish this "world's shortest course" were longer? Want to suggest a tip I should have added?