Showing posts with label gene editing. Show all posts
Showing posts with label gene editing. Show all posts
Sunday, November 30, 2025
Monday, August 25, 2025
Tuesday, July 29, 2025
Monday, September 23, 2024
Friday, September 1, 2023
Tuesday, July 4, 2023
Monday, December 5, 2022
Monday, May 18, 2020
AI: Maximizing the Potentials, Minimizing the Perils
It’s easy to see both the up- and
downsides of artificial intelligence.
Just a few upsides: more accurate
medical diagnosis, safe, fast automated vehicles, AI-driven instruction that
ever adapts its style and pace based on the student’s ongoing performance.
On the downside, luminaries such as Bill
Gates and Elon Musk worry that self-teaching AI computers could get smart
enough that humans won’t be able to stop them from nefarious ends.
It would seem that, per Stuart
Russell, author of Human Compatible, that we optimize risk/reward if we take
two steps: 1. Don’t let the computer “know” the goal of the software. 2. Block
the computer from making decisions beyond a certain magnitude—that when
implications of a decision go beyond a certain point, human override is
required. It’s kind of like the car salesperson who has discretion to give a 10
percent discount, but if more seems required, the boss must approve.
Another fear about AI is that an evil
individual or entity could use it to nefarious ends. A few examples: release a
murderous virus into the water supply, threaten to close down the electric grid
unless paid a zillion dollars, or develop an algorithm for manipulating people
into voting for Candidate X. (Whoops, that already pretty-much exists.) Of
course, most powerful things, notably nuclear energy, could be used
cataclysmically, yet most experts conclude that, rather than prohibit it, it’s
wiser to install in-computer and human oversight.
A similarly moderate stance could
apply to genomic research. On the upside it could better address such diseases
as cancer, diabetes, and cardiovascular disease and create drought-resistant-,
high-protein, and insect-repellant crops. Gene editing might eventually be used to create a super-intelligent human. Yes,
that person’s brainpower could be used for social good but what if the
gene-editing also caused him or her to have to live in physical pain? Or the
person could use the hyper-intelligence for personal gain even if it causes
great pain to the world. Again, it would seem that regulation, both built-in and legal might yield the risk/reward sweet spot.
What worries me is that such
restrictions may move such research to jurisdictions that have looser restrictions. For
example, the worldwide consensus has been that for now at least, gene editing be conducted only
for research, not clinically. He Jiankui defied that by using CRISPR to edit
the embryos of two recently born twin girls in what he said was an effort
to prevent them from contracting HIV. Russian scientist Denis Rebrikov
is planning to insert a gene into an embryo that would enable deaf couples to
produce hearing babies. Geneticist Bing Su has inserted a gene for brain
size, which is correlated moderately with intelligence. So, in this big world of ours, amid ever
advancing gene editing tools, it seems quite likely that, given the huge
stakes—even a country or non-state-actor creating an army of supergeniuses—that
restrictions would move some non-complying research underground.
En toto, it’s probably wise to
establish restrictions on AI: laws, professional standards, and, more
difficult, building-in limitations to AI software: forcing them to switch off
when the stakes are great or the implications unclear. Social norms and fear of
punishment will facilitate research that has a positive risk-reward ratio while
restraining less advisable research. Outright bans would likely yield worse
net results, as occurred when religion restricted scientific
research in the Dark Ages. It seems we must accept that the perfect is the
enemy of the good. Despite the likely excesses, it seems wise to bet on
humankind, that, net, we’ll probably derive positive effects from AI. It
certainly will be interesting to watch.
Labels:
artificial intelligence,
gene editing
Thursday, November 1, 2018
What Will Happen to the "Bottom Half?"
Predictions vary as to the percent of jobs that will be lost to automation, offshoring, and gigging but it’s likely to be between 20 and 60 percent within the next decade or two.
Consensus is that much of the remaining decent-paying employment will demand ever more brainpower, technical chops, and communication skills. And with so many applicants available, employers will be able to insist also on people who are likeable, reliable, enthusiastic and healthy.
The Big Question is, what’s going to happen to the many millions of people who don’t get hired for those jobs? I fear that things will be different from previous technological waves in which new technologies, net, created more new jobs. I predict that because so much of the future economy will be based on digital products and services, which can be produced by the millions with a push of a button.
My PsychologyToday.com article today describes what will likely be a problemed existence for the "bottom half" and possible approaches to ameliorating the situation.
Consensus is that much of the remaining decent-paying employment will demand ever more brainpower, technical chops, and communication skills. And with so many applicants available, employers will be able to insist also on people who are likeable, reliable, enthusiastic and healthy.
The Big Question is, what’s going to happen to the many millions of people who don’t get hired for those jobs? I fear that things will be different from previous technological waves in which new technologies, net, created more new jobs. I predict that because so much of the future economy will be based on digital products and services, which can be produced by the millions with a push of a button.
My PsychologyToday.com article today describes what will likely be a problemed existence for the "bottom half" and possible approaches to ameliorating the situation.
Labels:
automation,
decline in jobs,
gene editing
Saturday, February 3, 2018
How the Earth Got Conquered in 2078: A look at genetic enhancement
Genetic enhancement is seen by some as a savior, by others as a horror. I offer an optimistic vision in my PsychologyToday.com article today.
Labels:
gene editing,
genetic enhancment
Sunday, June 18, 2017
Enhance? A short-short story about genetically enhancing intelligence.
A May 22, 2017 New York Times headline reads: “In ‘Enormous Success,’ Scientists Tie 52 Genes to Human Intelligence."
A week later, the Journal of Cellullar Bioechemistry chronicled the enormous progress and potential in gene editing.
Such research suggests that in a decade or two, parents may have the option of having their sperm and eggs genome-edited to ensure their child has high or at least normal intelligence.
As my PsychologyToday.com contribution today, I offer a short-short story that explores one possible implication.
A week later, the Journal of Cellullar Bioechemistry chronicled the enormous progress and potential in gene editing.
Such research suggests that in a decade or two, parents may have the option of having their sperm and eggs genome-edited to ensure their child has high or at least normal intelligence.
As my PsychologyToday.com contribution today, I offer a short-short story that explores one possible implication.
Labels:
augmenting intelligence,
gene editing,
intelligence
Tuesday, August 23, 2016
Sunday, April 3, 2016
On Human Genetic Augmentation
New gene editing technologies such as Crispr have moved genetic enhancement from science fiction to reality.
In my PsychologyToday.com article today, I interviewed a preeminent expert in the field, Harvard's George Church, on the promise and perils.
In my PsychologyToday.com article today, I interviewed a preeminent expert in the field, Harvard's George Church, on the promise and perils.
Labels:
gene editing,
gene therapy,
genetic augmentation
Wednesday, February 3, 2016
What's New in Neuropsychology?
Sure, many of today's "exciting findings" will become tomorrow's blind
alleys, but the quantity, quality, and centrality of the new neuropsychology research findings boosts my hope that we'll finally get those breakthrough cures and even
ways to make us better "normals."
I briefly describe the current crop of research findings in my PsychologyToday.com article today.
I briefly describe the current crop of research findings in my PsychologyToday.com article today.
Labels:
depression,
gene editing,
intelligence,
neuropsychology,
schizophrenia
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